ochsenbein lab -
tumor immunology
& cancer stem cells

News

May 2017

We would like to congratulate Carla Ruckstuhl for her successfull PhD defense and wish her all the best for her future career

The papers "The multi-kinase inhibitor Debio 0617B reduces maintenance and self-renewal of primary human AML CD34+ stem/progenitor cells" and "CD70 reverse signaling enhances NK cell function and immunosurveillance in CD27-expressing B-cell malignancies" were published in Molecular Cancer Therapeutics and Blood

March 2017

We would like to welcome our new technician Tanja Chiorazzo and wish her a good start.

February 2017

Dr. Carsten Riether and Dr. Christian Schürch were awarded with a Pfizer Award 2017 for their work researching the combination treatment of imatinib and CD70/CD27 blockade to eradicate leukemia stem cells in CML.

Press release Pfizer Award

January 2017

The paper "CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia" was publisched in Journal of Experimental Medicine on 28. December 2016

Furthermore, based on the discoveries from the publication mentioned above, a first clinical trial testing the clinical efficacy of an antibody blocking CD70 activity in AML patients is underway

Press release Insel Spital

Merry Christmas and a Happy New Year!

September 2016

Mohamad Al-Sayed will be leaving our resarch group by the end of this month. We wish him all the best for his future career!

August 2016

We are happy to welcome Pascal Näf back to the lab and wish him a fruitfull start with his PhD project.

Also we would like to welcome are two new masterstudents Visar Vela and Nils Kallen.

April 2016

Prof. Adrian Ochsenbein and Prof. Markus Manz from Zürich were awarded with the Otto-Naegeli Price ex aequo.

Press release

March 2016

Mohamad Al Sayed had a successfull PhD defense and we congratulate him on his success. He will continue working in the lab for another 6 month to finsh up some open projects. But we already wish him all the best for his future career

Also Pascal Näf finshed his masterthesis succesfully and we are happy to say that he will be re-joining our lab in August for a PhD.

Februar 2016

We would like to congratulate Raissa Vargas for the succesfull defense of her masterthesis and wish her all the best for her future career.

Merry Christmas and a Happy New Year!

December 2015

Sadly Anne-Laure Huguenin and Daniela Korner have left the lab. However, we thank them for their great work and wish them all the best for their futures.

On the other hand we can also welcome two new labmembers: Ursina Lüthi our new lab technician and Thomas Gschwend who started with his MD,PhD project.

August 2015

We welcome Magdalena Hinterbrandner back to the lab and wish her a successful start with her PhD project.

We also welcome Pascal Näf our new master student in biomedical sciences and wish him also success with his project.

July 2015

The paper "Tyrosine kinase inhibitor-induced CD70 expression mediates drug resistance in leukemia stem cells by activating Wnt Signaling" was publisched in Science Translational Medicine on 29. July 2015

June 2015

Thomas Gschwend was awarded the Swiss MD-PhD Scholarship for 3 years from the Swiss National Science Foundation to perform their MD-PhD in our group. We thank the funders for supporting our future student and congratulate Thomas for his achievement!

February 2015

The paper "Blocking PD-1 in combination with adoptive cytotoxic T cell transfer eradicates CML stem cells" was publisched in Leukemia on 4. February 2015

We congratulate Magdalena Hinterbrandner for successfully completing her master thesis and we're looking forward to welcoming her back as a PhD student in August

January 2015

We congratulate Carsten Riether for his successful habilitation. Furthermore togeather with Christian Schürch he was awarded the Young Investigators Award at the Brupbacher Symposium

Merry Christmas and a Happy New Year!

December 2014

Raissa Vargas has started her project for the master thesis. We are happy to welcome her in our research group and wish her a successful start with her project.

Dr. Riether received a personal grant from the Sassella Foundation.

October 2014

Prof. Adrian Ochsenbein was awarded with one of the Swiss Bridge Awards 2014 for his work researching the interaction of the immune system with cancer stem cells.

We also want to congratulate Prof. Laurence Zitvogel from the Institute Gustave Rousssy in France who was awarded with a second Swiss Bridge Award.

Press release Insel

Press release Swiss Bridge

August 2014

Vera Formanowski has started working on the research project for her master thesis. We are happy to welcome her in our research group and wish her a successful start with her project.

July 2014

The review "Regulation of hematopoietic and leukemic stem cells by the immune system" by Riether C., Schürch C. and Ochsenbein A.F. has been published in Cell Death & Differentiation on 4. July 2014

June 2014

Dr. Sabine Höpner recieved a grant from the "Stiftung zur Krebsbekämpfung"

May 2014

Tamara Hilmenyuk left our Lab for a Postdoc position in Melbourne. We wish her a good start in Down Under and all the best for her future!

Dr. Ramin Radpour recieved a grant from the Stiftung für klinisch experimentelle Krebsforschung

April 2014

Elias Bührer started with his MD, PhD project. We wish Elias a good start and lots of success!

March 2014

Magdalena Hinterbrandner has started with her project for the master thesis. We are happy to welcome her in our research group and wish her a good start.

February 2014

The paper "Cytotoxic CD8 T Cells Stimulate Hematopoietic Progenitors by Promoting Cytokine Release from Bone Marrow Mesenchymal Stromal Cells" by Schürch C., Riether C. and Ochsenbein A.F. has been published in Cell Stem Cell on 20. February 2014

Read press releases: Inselspital and University of Bern

Linda Drück has finished her internship. We wish her all the best for her future plans.

December 2013

We are proud to announce that an article of our lab by Schürch, Riether and Ochsenbein has been accepted for publication in the No.1 stem cell journal Cell Stem Cell.

Our review "Dendritic cell-based immunotherapy for myeloid leukemias" has been accepted and published online in "frontiers in immunology".

Dr. Riether received a personal grant from the Sassella Foundation.

November 2013

Dr. Schürch won the Hemmi Award for Clinical Research.

Drs. Schürch and Riether received a grant from the Mobiliar Jubiläumsstiftung.

Drs. Ochsenbein, Riether and Schürch received a grant from the Stiftung für klinisch-experimentelle Tumorforschung Bern.

October 2013

Dr. Ramin Radpour, started working in our lab. We wish Ramin a good start and lots of success!

September 2013

Dr. Sabine Höpner received a grant from the Bernische Krebsliga. We thank the funders for their contribution and congratulate Sabine for her achievement!

Drs. Riether and Schürch received a grant from the the Fondazione per la ricerca sulla trasfusione e sui trapianti. Congratulations!

Dr. Christian Schürch won the 3rd oral presentation prize at the 25th European Congress of Pathology in Lisbon, Portugal. Congratulations!

Dr. Carsten Riether successfully finished his Certificate of Advanced Studies (CAS) in Research Management. Congratulations!

August 2013

The 15th International Congress of Immunology took place in Milan, Italy. It was a great platform to present our results and to get an update of the field. Our lab presented of 2 oral presentations and 3 posters.

Mohamad Al Sayed successfully passed his second year exam. Congratulations!

Drs. Schürch and Riether received a grant from the Monika Kutzner-Stiftung. We thank the funders for their contribution!

July 2013

Michael Amrein and Elias Bührer both were awarded the Swiss MD-PhD Scholarship for 3 years from the Swiss National Science Foundation to perform their MD-PhD in our group. This is a huge success for our lab! We thank the funders for supporting our future students and congratulate Elias and Michael for their achievement!

The Ochsenbein Lab summer party took place at Grandson, Lake Neuchâtel. We enjoyed a sunny afternoon at the lake, wakeboarding, playing football and volleyball and having fun! Big thanks also to Mrs. Ochsenbein who prepared the dinner!

June 2013

Harriet Falk, Msc, joined our lab for an internship. We wish her a good start and lots of success!

May 2013

Dr. Tamara Hilmenyuk successfully defended her PhD thesis entitled "Malignant Lymphoma B cells induce dysfunctional cytotoxic T cells". Congratulations, well done!

Drs. Carsten Riether and Christian Schürch won the "Bern Immunology Club Award" for the best paper in 2012. Congratulations!

Dr. Tamara Hilmenyuk received an "Early Postdoc Mobility" fellowship from the Swiss National Science Foundation for her project "Functional and structural characterisation of Type-2 NKT T cell receptors" at the University of Melbourne, Australia. Congratulations, and we wish her lots of success!

Our lab received grants from the San Salvatore Foundation (Drs. Ochsenbein, Riether and Schürch) and the Wolfermann-Nägeli-Stiftung (Drs. Schürch and Riether). We thank the funders for supporting our research!

April 2013

The Annual Meeting of the Swiss Society for Allergology and Immunology took place in Bern. Our group presented 2 orals and 3 posters. Read more

Drs. Schürch and Riether received a grant from the Stiftung Krebs-Hilfe. We thank the funders for their contribution!

March 2013

We have an open postdoc position available. Read more

February 2013

Our article "Cytotoxic T cells induce the proliferation of chronic myeloid leukemia stem cells by secreting Interferon-g" by Schürch and Riether et al. is now available online at the Journal of Experimental Medicine. Read more: J Exp Med

January 2013

Dr. Schürch won the GCB Award for the Best Thesis 2012. Congratulations!

Dr. Schürch received a personal grant from the Dr. Hans Altschüler-Stiftung. Congratulations!

Our article "Cytotoxic T cells induce the proliferation of chronic myeloid leukemia stem cells by secreting Interferon-g" by Schürch and Riether et al. has been accepted by the Journal of Experimental Medicine.

December 2012

Dr. Riether received a personal grant from the Fondation BIOS pour la recherche, and Dr. Schürch received two personal grants from the Fondazione Dr. Carlo Gianella and from the Stiftung Dr. Hans Krummen. Congratulations!

Swiss Television SRF "Puls" visited our lab and conducted an interview with Prof. Ochsenbein. See the full interview here

November 2012

Our review "From "Magic Bullets" to Specific Cancer Immunotherapy" has been accepted by Swiss Medical Weekly Journal.

Dr. Riether received a personal grant from the Sassella Foundation, and Dr. Schürch received his Certificate of Advanced Studies in Higher Education. Congratulations!

October 2012

We have 2 elective module positions in slot 2 (22.04.-10.05.2013) available next year. Please visit List of Proposals and Announcement Ochsenbeinlab

September 2012

The 3rd European Congress of Immunology took place in Glasgow, UK. ECI 2012 Homepage

It was a great platform to present our results and to get an overview of the field. We take the opportunity to thank the funding agencies for the travel grants they provided (Ms. Hilmenyuk, DCR travel grant; Dr. Riether, EFIS travel grant; Dr. Schürch, SGAI travel grant).

August 2012

The Ochsenbein Lab summer party took place at Grandson, Lake Neuchâtel. We enjoyed a sunny afternoon at the lake, wakeboarding, playing football and having fun! Big thanks also to Mrs. Ochsenbein who prepared the dinner! Some impressions

Diego Lopez, biomedical sciences student, begins his master thesis in our lab. We wish him a good start and lots of success!

July 2012

Our author's opinion on "Modulating CD27 signaling to treat cancer" has been accepted by OncoImmunology Journal. Read more

June 2012

We have an open postdoc position available. Read more

May 2012

Cancer Research accepted our article "CD27-signaling increases the frequency of regulatory T cells and promotes tumor growth" for publication. Read more: Cancer Res Published OnlineFirst May 24, 2012

Prof. Ochsenbein and Dr. Riether recieved a personal grant for Dr. Riether from the "Novartis Stiftung für medizinisch-biologische Forschung", and Dr. Schürch received a research grant from the "SwissLife Jubiläumsstiftung". Congratulations!

April 2012

Christoph Flury, medical student, joined our lab for his master thesis and medical dissertation. We wish him a good start and lots of success!

March 2012

Dr. Christian Schürch, MD, successfully defended his PhD thesis entitled "Immune surveillance of cancer stem cells in chronic myeloid leukemia" with the final mark "summa cum laude (6)". Congratulations!

Carla Ruckstuhl started her PhD thesis in our lab. We wish her lots of success!

February 2012

Dr. Sabine Höpner, PhD, postdoc and Jennifer Leona Scheffler, lab technician, joined our lab. We wish them a good start and lots of success!

Carla Ruckstuhl and Sarah Gabriel, master students of science in biomedical sciences, successfully finished their master theses. Carla Ruckstuhl will continue for a PhD thesis in our lab, and Sarah Gabriel moves to Zürich for a PhD thesis. We wish both of them lots of success in the continuation of their careers and thank them for their contributions.

January 2012

Our article "CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression" is available online on the official homepage of the JCI. Read more

December 2011

Dr. Riether received a personal grant from the Sassella Foundation. Congratulations!

November 2011

The Journal of Clinical Investigation accepted our article "CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression" for publication.

October 2011

Prof. Adrian F. Ochsenbein received the Robert Wenner-Prize from the Swiss Cancer League. Congratulations! Read more

Dr. Schürch and Dr. Riether received two research grants from the Ehmann Stiftung Savognin and from the Fondazione per la ricerca sulla trasfusione e sui trapianti

September 2011

Prof. Adrian F. Ochsenbein is promoted to Extraordinary Professor (Extraordinarius) for Medical Oncology. Congratulations!

Our homepage is getting into shape. We thank Christian Forney for his excellent knowledge and his dedication!

August 2011

Sarah Gabriel, student of biomedical sciences, begins her master thesis in our lab. We wish her a good start and lots of success!

July 2011

Carla Ruckstuhl, student of biomedical sciences, begins her master thesis in our lab. We wish her a good start and lots of success!

June 2011

Dr. Schürch received a research grant from the "SwissLife Jubiläumsstiftung". Congratulations!

Thomas Gschwend, medical student, begins his master thesis in our lab. We wish him a good start and lots of success!

April 2011

Prof. Adrian F. Ochsenbein is promoted Chief physician (Chefarzt) of Medical Oncology at the Inselspital, University Hospital Bern.